Incidences of side effects like vomiting (n = 286; RR 0.65, 95 % CI: 0.19 to 2.25), diarrhea (n = 286; RR 2.92, 95 % CI: 0.31 to 27.71), and rash (n = 286; RR 2.92, 95 % CI: 0.12 to 71.03) were found to be rare and statistically comparable between groups. 2010;(1):CD001146. Canadian Paediatric Society, Fetus and Newborn Committee. 2006;(4):CD004592. The authors concluded that the role of massage therapy in the management of NNH was supported by the current evidence. Aetna considers massage therapy experimental and investigational for the treatment ofneonatal hyperbilirubinemia because its effectiveness has not been established. These researchers used the standard methods of the Cochrane Collaboration and its Neonatal Review Group for data collection and analysis. One study reported a significant reduction in the risk of hyperbilirubinemia and rate of treatment with phototherapy associated with enteral supplementation with prebiotics (RR 0.75, 95 % CI: 0.58 to 0.97; 1 study, 50 infants; low-quality evidence). These investigators randomly assigned 1,974 infants with extremely low birth weight at 12 to 36 hours of age to undergo either aggressive or conservative phototherapy. } Approximately 60% of term babies and 85% preterm babies will develop clinically apparent jaundice, which classically becomes visible on day 3, peaks days 5-7 and resolves by 14 days of age in a term infant and by 21 days in the preterm infant. A total of 150 term Caucasian neonates, 255 measurements of TSB and TcB concentration were obtained 2 hours after discontinuing phototherapy. Cochrane Database Syst Rev. The therapy may be in the form of a lamp, light panel, or special light blanket. Jaundice, Coombs, and Phototherapy AAP Clinical Practice Guideline - Summary Bhutani Nomogram Guidelines for Phototherapy FAQs About Phototherapy This code may be reported only once per day and by only one physician. Mean TSB (120 +/-19 mol/L versus 123 +/- 28 mol/L, DXM versus placebo, respectively) and maximum TSB (178 +/- 23 mol/L versus 176 +/- 48, DXM versus placebo, respectively) concentrations were similar. Attempt to improve transcutaneous bilirubinometry: A double-blind study of Medick BiliMed versus Respironics BiliCheck. In search of a 'gold standard' for bilirubin toxicity. This document addresses the use of home phototherapy and the devices used for the treatment of neonatal jaundice that is physiologic (that is, non-pathologic) in nature. All that is needed is watchful waiting. Treatment of unconjugated hyperbilirubinemia in term and late preterm infants. Liu J, Long J, Zhang S, et al. New perspectives on neonatal hyperbilirubinemia. Two hundred years ago, newborns would have been placed on blankets in the sun for newborn jaundice. Single versus double volume exchange transfusion in jaundiced newborn infants. This is caused by a small opening in the abdominal muscles that abdominal contents (e.g., fluid, abdominal lining) spill through. Aetna's policy on treatment of hyperbilirubinemia in infants is adapted from guidelines from the American Academy of Pediatrics. Copyright Aetna Inc. All rights reserved. Subsequent days of critical care to the critically ill neonate are reported per day with code 99469. There are implications for future healthcare needs (e.g., having a specialty consult ordered prior to discharge). Do I Use 25 or 59 for Same-day Assessment and E/M? 1992;89:823-824. Pediatrics. 2011;12:CD007969. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Moreover, they stated that routine use of probiotics to prevent or treat neonatal jaundice cannot be recommended; large well-designed trials are needed to confirm these findings. text-decoration: underline; Fractured clavicles are usually noted by the pediatrician on the newborn evaluation, but do not meet the definition of clinical significance. Place the thermometer in your newborn's armpit while the phototherapy lights are on. 202;11(1):e040182. Lacrimal ducts are the drainage system for fluid that lubricates the eye. Torres-Torres M, Tayaba R, Weintraub A, et al. There were no probiotic-related adverse effects. li.bullet { No studies met the inclusion criteria for this review. Phototherapy was well-tolerated without evidence of significant photo-damage or photo-carcinogenicity. Okwundu CI, Okoromah CA, Shah PS. padding-bottom: 4px; Discharge normal newborn day 3 _____ 2. } Prebiotics for the prevention of hyperbilirubinaemia in neonates. All of the outcome measures should be monitored by a standardized effective report system in clinical trials and rare serious adverse reaction could be observed through epidemiological studies. phototherapy in the home, applied by a . Do not percuss over the backbone, breastbone, or lower two ribs. Valaes T. Problems with prediction of neonatal hyperbilirubinemia. 2019;8:CD012731. Inpatient treatment may be medically necessary for pre-term infants who present with a TSB greater than or equal to 18 mg/dL. Clin Pediatr (Phila). Now, newborns are checked with a transcutaneous bilirubinometer, and the pediatrician reviews standard laboratory blood screenings. foam closure strips for metal roofing | keokuk, iowa arrests newington high school football coach 0 Cochrane Database Syst Rev. Moreover, these investigators stated that infants with bilirubin levels greater than 25 mg/dL, those who are not responding to phototherapy, and those with evidence of acute bilirubin encephalopathy should be treated with exchange transfusion, with initiation based on an infants age in hours and neurotoxicity risk factors. In a Cochrane review, Thomas et al (2007) stated that neonates from isoimmunized pregnancies have increased morbidity from neonatal jaundice. Rates of death in the aggressive-phototherapy and conservative-phototherapy groups were 24 % and 23 %, respectively (relative risk, 1.05; 95 % CI: 0.90 to 1.22). Neonatology. Saunders Co.; 2000:513-519. display: block; When the pediatrician spends additional time explaining the skin condition, and the findings affect the episode of care, it should be coded on professional encounters. #closethis { Only 1 study met the criteria of inclusion in the review. width: 100%; Usually, the nurses pin the sleeve of the affected arm to the body of the newborns t-shirt. Two reviewers independently assessed studies for inclusion, and discrepancies were resolved with consensus. Practice parameter: Management of hyperbilirubinemia in the healthy term newborn. US Preventive Services Task Force; Agency for Healthcare Research and Quality. Various trials in pregnant women who were not isoimmunized but had other risk factors for neonatal jaundice have shown a reduction in need for phototherapy and exchange transfusion by the use of antenatal phenobarbital. They stated that a Cochrane review of clofibrate (2012) and metalloporphyrins (2003) found that when added to phototherapy, these medications significantly decreased serum bilirubin levels and duration of phototherapy. Clin Pediatr (Phila). Secondary outcomes included incidence of jaundice, TSB level at 24, 48, 72, 96hours, and day 7, duration of hospital stay, and adverse effects (e.g., probiotic sepsis). cpt code for phototherapy of newborn. The authors concluded that phototherapy significantly interfered with the accuracy of transcutaneous bilirubinometry; TcB measurements performed 2 hours after stopping phototherapy were not reliable, even if they were performed on the unexposed body area. At the well-baby check, report K42.9 Umbilical hernia without obstruction or gangrene if the condition is addressed (not merely noted in the documentation). In pre-planned subgroup analyses, the rates of death were 13 % with aggressive phototherapy and 14 % with conservative phototherapy for infants with a birth weight of 751 to 1,000 g and 39 % and 34 %, respectively (relative risk, 1.13; 95 % CI: 0.96 to 1.34), for infants with a birth weight of 501 to 750 g. The authors concluded that aggressive phototherapy did not significantly reduce the rate of death or neurodevelopmental impairment. cpt code for phototherapy of newborn Last Review 2009;124(4):1172-1177. Furthermore, an UpToDate review on "Evaluation of unconjugated hyperbilirubinemia in term and late preterm infants" (Wong and Bhutani, 2017) states that "TcB measurements are not reliable in infants undergoing phototherapy. The extracted information of RCTs should include efficacy rate, serum total bilirubin level, time of jaundice fading, duration of phototherapy, duration of hospitalization, adverse reactions. Zinc sulfate showed no influence on phototherapy requirement (OR=0.90; 95 % CI:0.41 to 1.98; p=0.79), but resulted in significantly decreased duration of phototherapy (MD=-16.69hours; 95 % CI:-25.09 to -8.3hours; p<0.0001). registered for member area and forum access. More commonly seen in the documentation are: Without a diagnosis, abnormal results of routine screenings should not be coded unless the pediatrician states the abnormal results have implications for future healthcare. } An example is hemangiomas (e.g., strawberry hemangiomas), which do not impinge on vital structures and are not located in the periorbital area, lip, neck, or sacral region. Data sources included PubMed, Embase, Cochrane library, China National Knowledge Infrastructure, China Biology Medicine, VIP Database, and Wanfang Database. Am Fam Physician. Some watchful waiting conditions include: Some conditions happen more frequently in premature newborns such as cryptorchidism and umbilical hernias. Per the ICD-10-PCS Official Guidelines for Coding and Reporting, only clinically significant conditions are reported. Screening had good ability to detect hyperbilirubinemia: reported area-under-the-curve values ranged between 0.69 and 0.84, and reported sensitivities and specificities suggested similar diagnostic ability. London, UK: BMJ Publishing Group;November 2006. 2007;12(5):1B-12B. However, that is not always the case. 2019;32(1):154-163. No association was found between the UGT1A1*28 allele and extreme hyperbilirubinemia. Garg BD, Kabra NS, Balasubramanian H. Role of massage therapy on reduction of neonatal hyperbilirubinemia in term and preterm neonates: A review of clinical trials. Neonatal hyperbilirubinemia: An evidence-based approach. Metalloporphyrins in the management of neonatal hyperbilirubinemia. Chu and colleagues (2020) stated that phototherapy devices have been found to be an effective method for treating neonatal hyperbilirubinemia. Even if it meets the technical meaning of conjunctivitis (inflammation of the conjunctiva), it isnt contagious; its self-limiting and does not affect medical decision-making, so it cannot be coded on the pediatricians encounter. Approximately 10 to 20 percent of newborns have an umbilical hernia. The RR or MD with a 95 % CI was used to measure the effect. The code is valid for the year 2023 for the submission of HIPAA-covered transactions. E0202 is the HCPC for phototherapy that would normally be billed by the hospital/dme provider. Use total bilirubin. It is also important to note that thereare serious health risks associatedwith corticosteroid therapy. The primary outcomes were TSB on 3 days and 7 days, the incidence of hyperbilirubinemia. Aetna considers transcutaneous bilirubin devices for evaluating hyperbilirubinemia in term and near-term infants while undergoing phototherapy experimental and investigational becasue this approach is not reliable in infantsin this setting. Randomized controlled trials were eligible for inclusion if they enrolled neonates (term and pre-term) to whom oral zinc, in a dose of 10 to 20 mg/day, was initiated within the first 96 hours of life, for any duration until day 7, compared with no treatment or placebo. Swelling in such a hydrocele is uniform, over time, until the fluid is absorbed by the body. Meta-analysis of the 3 studies showed a significant increase in stool frequency in the prebiotic groups (MD 1.18, 95 % CI: 0.90 to 1.46, I = 90 %; 3 studies, 154 infants; high-quality evidence). Front Pharmacol. Gartner LM, Gartner LM,. 2005;17(2):167-169. Data were statistically extracted and evaluated using RevMan 5.3 software. And immature lacrimal glands mature, hydroceles close, and hip joint motion usually improves without need for intervention. Clinical evaluation (e.g., specialty consult during the hospitalization); Therapeutic treatment (e.g., bili lights for clinically significant neonatal jaundice); Diagnostic procedures (e.g., ultrasound due to sacral dimple); Extended length of hospital stay (e.g., beyond the average for the MS-DRG); Increased nursing care and/or monitoring (e.g., neonatal intensive care unit); or. Reference Number: CP.MP.150 Coding Implications Date of Last Revision: 10/22 Revision Log See Important Reminder at the end of this policy for important regulatory and legal information. Schuman AJ, Karush G. Fiberoptic vs conventional home phototherapy for neonatal hyperbilirubinemia. Bhutani VK; Committee on Fetus and Newborn; American Academy of Pediatrics. There is insufficient evidence to support the use of metalloporphyrins (e.g., stannsoporfin (tin mesoporphyrin), Stanate, WellSpring Pharmaceutical Corporation, Neptune, NJ) for the treatment of neonatal jaundice. N Engl J Med. For more information about cryptorchidism, visit: ncbi.nlm.nih.gov/pubmed/10932966. on Watchful Waiting:Collecting Newborn Information, Watchful Waiting:Collecting Newborn Information, Tech & Innovation in Healthcare eNewsletter, Capture Active Duty Diagnoses with DoD Unique Codes, Finally Tobacco Use That Isn't a Mental Health Issue, Know Your Payer to Make the Most of Modifier 24, Modifier 25 for E/M on the Day of an Injection Procedure. Do not subtract direct (conjugated) bilirubin. 1993;32:264-267. 2004;114(1):297-316. There are 4 chief Current Procedural Terminology (CPT) codes for reporting phototherapy services: (1) 96900: actinotherapy (UV light treatment); (2) 96910: photochemotherapy, tar, and UVB (Goeckerman treatment) or petrolatum and UVB; (3) 96912: photochemotherapy and PUVA; and (4) 96913: photochemotherapy (Goeckerman and/or PUVA) for severe at the end of this policy for important regulatory and legal information. When no additional resources are used, this is not coded on the inpatient record, and is part of the pediatricians well-baby check. However, the results remain controversial. This study compared oral zinc with placebo. J Matern Fetal Neonatal Med. Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia. Santa Barbara, CA: Elsevier Saunders; 2011. tradicne jedla na vychodnom slovensku . It affects approximately 2.4 to 15 % of neonates during the first 2 weeks of life. Guidelines from the American Academy of Pediatrics (AAP, 2004)on management of hyperbilirubinemia in thenewborn infantstate that "Measurement of the glucose-6-phosphate dehydrogenase (G6PD) level is recommended for a jaundiced infant who is receiving phototherapy and whose family history or ethnic or geographic origin suggest the likelihood of G6PD deficiency or for an infant in whom the response to phototherapy is poor(evidence quality C: benefits exceed harms)". map of m6 motorway junctions. All 3 review authors independently assessed study eligibility and quality. 2016;36(10):858-861. The authors concluded that limited low-quality evidence indicated that probiotic supplementation may reduce the duration of phototherapy in neonates with jaundice. Usually, procedures coded: Low-cost, low-risk screening and prevention procedures usually are not coded. 2013;89(5):434-443. J Fam Pract. Therefore, well-designed, large randomized, double blind, placebo-controlled trials would be needed to further confirm the efficacy of probiotics. The efficacy of intravenous fluid supplementation for neonatal hyperbilirubinemia: A meta-analysis of randomized controlled studies. This indicated that cure may have been achieved in a minority of patients. list-style-type: upper-roman; These usually heal and resolve on their own. Sacral dimples without diagnostic services, such as diagnostic imaging, are not coded on inpatient records. .strikeThrough { For instance, abnormal findings on screenings for example, newborn hearing screening or lab screenings are not coded in the inpatient record, unless: Here are several watchful waiting findings to consider. A randomized, triple-blind, placebo-controlled trial of prophylactic oral phenobarbital to reduce the need for phototherapy in G6PD-deficient neonates. In a Cochrane review, Gholitabar et al (2012) examined the safety and effectiveness of clofibrate in combination with phototherapy versus phototherapy alone in unconjugated neonatal hyperbilirubinemia. Typically, no extra resources are required during the newborn hospitalization, so do not code the condition. For well infants 35 - 37 6/7 wk, can adjust TSB levels for intervention around the medium risk line. It may not display this or other websites correctly. Although an undescended testicle usually is described as palpable or impalpable, also get the location, if you can. For the term neonates, there were significantly lower bilirubin levels in the clofibrate group compared to the control group after both 24 and 48 hours of treatment with a weighted mean difference of -2.14 mg/dL (95 % CI: -2.53 mg/dL to -1.75 mg/dL) (-37 mol/L; 95 % CI: -43 mol/L to -30 mol/L] and -1.82 mg/dL (95 % CI: -2.25 mg/dL to -1.38 mg/dL) (-31 mol/L; 95 % CI: -38 mol/L to -24 mol/L), respectively. Documentation should include approximate time spent face-to-face with the family and patient, notation of time spent in counseling, and context of counseling. J Pediatr Gastroenterol Nutr. Can Nurse. Phototherapy in the home setting. For most newborns, the transition from fetal to newborn blood simply involves watchful waiting. It is an option to provide conventional phototherapy in hospital or at home at TSB levels 2 - 3 mg/dL below those shown, but home phototherapy should not be used in any infant with risk factors. As a contributor you will produce quality content for the business of healthcare, taking the Knowledge Center forward with your knowhow and expertise. De Luca D, Zecca E, Corsello M, et al. Both trials in preterm neonates and most of the trials in term neonates (5 trials) reported increased stool frequencies. Percussion should not cause red marks on your child. Learn how we are healing patients through science & compassion, Stanford team stimulates neurons to induce particular perceptions in mice's minds, Students from far and near begin medical studies at Stanford. The authors concluded that effects of screening on the rates of bilirubin encephalopathy are unknown. Aetna considersphototherapy medically necessary forterm andnear-term infantsaccording to guidelines published by the American Academy of Pediatrics (AAP). Mishra S, Cheema A, Agarwal R, et al. After the newborn begins to breath on his own, the fetal blood is destroyed and replaced with blood that works with lungs. 1995;96(4 Pt 1):727-729. Hulzebos CV, Bos AF, Anttila E, et al. TcB measurements obtained on the forehead, sternum, abdomen and covered lower abdomen were statistically compared with the corresponding TSB. Until the lacrimal ducts drain spontaneously, the pediatrician can show the parents a massage technique to use between the bridge of the nose and the inside corner of the affected eye. Sometimes, fluid builds up inside the lining, causing a hydrocele. With the common genotype as reference, the odds ratio of extreme hyperbilirubinemia was 0.87 (range of 0.68 to 1.13) for UGT1A1*28 heterozygotes and 0.77 (range of 0.46 to 1.27) for homozygotes. The authors found a moderate correlation between TcB and TSB during phototherapy with a marginal improvement in the post-phototherapy phase. list-style-type: decimal; The meta-analyses of 2 studies demonstrated a significant reduction in the length of hospital stay (MD -10.57 days, 95 % CI: -17.81 to -3.33; 2 studies, 78 infants; I = 0 %, p = 0.004; low-quality evidence). Policy Home phototherapy is considered reasonable and necessary for a full-term Only 1 study was able to show reduction in the mean TSB level and requirement of phototherapy with zinc, and the remaining studies did not report any positive effect. In utero, the fetus requires larger amounts of hemoglobin for oxygenation. Early corticosteroid treatment does not affect severity of unconjugated hyperbilirubinemia in extreme low birth weight preterm infants. } Codes 99478-99480 each are described as, "Subsequent intensive care, per day, for the evaluation and management of the recovering low or very low birth weight infant" with the code selected based. Codes for circumcision procedures include: When providing E/M services to other than normal newborns, choose the level of care based on the intensity of the service and status of the newborn. . Li and colleagues (2019) examined the associations between G6PD 1388 G>A, SLCO1B1 rs4149056 and BLVRA rs699512 variants and the risk of neonatal hyperbilirubinemia in a Chinese neonate population. Indian Pediatr. Suresh GK, Martin CL, Soll RF. 16th ed. Home phototherapy with the fiberoptic blanket. A condition does not need to be coded on the inpatient hospital encounter to be coded on the pediatricians hospital encounter. } 2002;3(1). In a Cochrane review, these investigators examined if administration of prebiotics reduces the incidence of hyperbilirubinemia among term and pre-term infants compared with enteral supplementation of milk with distilled water/placebo or no supplementation. 1998;101(1 Pt 1):25-31. Numerous skin findings may be noted, but are not coded in the inpatient record unless they are clinically significant. Participating providers are independent contractors in private practice and are neither employees nor agents of Aetna or its affiliates. 2008;359(18):1885-1896. Because it is a screening (not diagnostic), the test does not meet the definition of a diagnostic procedure or therapeutic treatment for a clinically significant condition. The results revealed that SLCO1B1 388 G>A is associated with an increased risk of neonatal hyperbilirubinemia (odds ratio [OR], 1.39; 95 % CI: 1.07 to 1.82) in Chinese neonates, but not in white, Thai, Latin American, or Malaysian neonates. Newman TB, Maisels MJ. San Carlos, CA: Natus Medical Inc.; 2002. When there is a diagnostic study, such as an ultrasound with no diagnosis, the justification for the diagnostic study is coded with R29.4 Clicking hip. The authors concluded that there are insufficient data from different countries on the use of clofibrate in combination with phototherapy for hyperbilirubinemia to make recommendations for practice. Sometimes, a parent declines prophylactic services such as the eye ointment and vaccinations. A total of 25 infants had been randomized into the DXM group; 29 into the placebo group. Indirect evidence from 3 descriptive uncontrolled studies suggested favorable associations between initiation of screening and decrease in hyperbilirubinemia rates, and rates of treatment or re-admissions for hyperbilirubinemia compared with the baseline of no screening. J Pediatr (Rio J). Support Lucile Packard Children's Hospital Stanford and child and maternal health, AAP Clinical Practice Guideline -- Full Version, Assessing Risk Based on Bilirubin Level -- "BiliTool", Infants who have not latched-on or nursed effectively for 12 hours, Infants supplemented more than once in 24 hours, Mothers with a history of breastfeeding failure, Antepartum mothers at risk of preterm delivery, AAP Clinical Practice Guideline - Summary. Nelson Textbook of Pediatrics. We are looking for thought leaders to contribute content to AAPCs Knowledge Center. Guidelines for Perinatal Care. The pooled estimates of correlation coefficients (r) during phototherapy were: covered sites 0.71 (95 % CI: 0.64 to 0.77, 11 studies), uncovered sites 0.65 (95 % CI: 0.55 to 0.74), 8 studies), forehead 0.70 (95 % CI: 0.64 to 0.75, 12 studies) and sternum 0.64 (95 % CI: 0.43 to 0.77, 5 studies). The smallest but significant difference between TSB and TcB was found on the lower abdomen. Casnocha Lucanova L, Matasova K, Zibolen M, Krcho P. Accuracy of transcutaneous bilirubin measurement in newborns after phototherapy. All the studies used zinc sulfate, only 1 study used zinc gluconate. 92586 Auditory evoked potentials for evoked response audiometry and/or testing of the central nervous system, limited There is no CPT code because these hospital screenings are usually done by hospital staff who are trained by an audiologist. Curr Opin Pediatr. The genotype of Gilbert syndrome, the UGT1A1*28 allele, causes markedly reduced activity of this enzyme, but its association with neonatal hyperbilirubinemia is uncertain and its relationship with extreme hyperbilirubinemia has not been studied. color: blue Kumar P, Chawla D, Deorari A. Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates. Transcutaneous bilirubinometry in the context of early postnatal discharge. Everything I am finding indicates this code is used for dermatological treatment not for jaundice. If separately documented in the mother's chart, you may report these services in addition to the services provided to the infant. Pediatrics. 2019;55(9):1077-1083. Chawla D, Parmar V. Phenobarbitone for prevention and treatment of unconjugated hyperbilirubinemia in preterm neonates: A systematic review and meta-analysis. The literature search was done for various RCTs by searching the Cochrane Library, PubMed, and Embase. So why would you not use one of the codes from 99221-99223 for the first day? One infant (1.6%) met all three AAP guideline criteria of being DAT-positive, bilirubin within 3 of exchange level, and rising bilirubin despite intensive phototherapy. Thomas JT, Muller P, Wilkinson C. Antenatal phenobarbital for reducing neonatal jaundice after red cell isoimmunization. Pediatrics. Pediatrics. Montreal, QC: CETS; October 2000. Phototherapy is the use of visible light to treat severe jaundice in the neonatal period. These investigators conducted a systematic review and meta-analysis to examine the safety and efficacy of zinc sulfate on hyperbilirubinemia among neonates. In: Nelson Textbook of Pediatrics. The correlation between TSB and TcB was found to be moderately close (r = 0.4 to 0.5). ICD-10 Restricts Same-day Sick and Well Visits. If the fractured clavicle does not use additional resources during the hospitalization (a safety pin is not additional resources), do not code the condition on the hospital encounter. BiliCheck variability (+/- 2 SD of the mean bias from serum bilirubin) was within -87.2 to 63.3 micromol/L, while BiliMed variability was within -97.5 to 121.4 micromol/L. French S. Phototherapy in the home for jaundiced neonates. Watchko and Lin (2010) noted that the potential for genetic variation to modulate neonatal hyperbilirubinemia risk is increasingly being recognized. The UGT1A1*28 allele was assessed in a case-control study of 231 white infants who had extreme hyperbilirubinemia in Denmark from 2000 to 2007 and 432 white controls. To determine if the administration of the anti-infective (e.g., erythromycin) externally to the eye (3E0CX2 Introduction of oxazolidinones into eye, external approach) is coded, check if your hospital has a policy on inpatient procedure collection. Code History 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-PCS) 2017 (effective 10/1/2016): No change First, because the value of jaundice fading in each guideline was different, the heterogeneity was high in time of jaundice fading. In a systematic review and meta-analysis, Chu and colleagues (2021) examined if intermittent phototherapy is more effective than continuous phototherapy in the treatment of neonatal hyperbilirubinemia.

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