Although several herbs have been proven to alter the mechanism of warfarin, there are not enough clinical trial data to prove the significance of those effects. Cancer Lett 2000;148:9-17. This holds true for ashwagandha. Unable to load your collection due to an error, Unable to load your delegates due to an error. View abstract. 2013;45(4):417-8. January 03, 2023 Office of Dietary Supplements. Therefore, it should be used cautiously with drugs used to treat diabetes, including: Just like with potential interactions between ashwagandha and diabetes drugs, there may be a potential issue with drugs used to treat high blood pressure as studies show ashwagandha mayhave blood-pressure-lowering effects. It is estimated that about one-third of adults in the United States use herbal supplements.1 These supplements are widely used, especially by patients with chronic conditions. Does letrozole interact with my other drugs? There is little evidence for its use as an "adaptogen." Ashwagandha contains chemicals that. An interaction impacts how a drug works and might increase or reduce the effects of the said medicine. You may need to have your blood clotting tests checked more frequently and may need a change in your anticoagulant dose. We recommend checking outLucid Super Coffee. Herb-drug interactions: a literature review. Can you take ashwagandha and Orilissa together? Speak with your doctor before combining valerian with or other medicines that also cause drowsiness or sedation, including: Avoid activities requiring mental alertness such as driving, operating hazardous machinery, or other dangerous activities until you know how the medications affect you. J Evid Based Complementary Altern Med. Last updated on July 14, 2022. View abstract. View abstract. Use birth control you can trust while taking this product. 2021 Feb 11;6(1):20. doi: 10.3390/jfmk6010020. J Ethnopharmacol 1998;62:209-14. Ge B, Zhang Z, Zuo Z. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. J Ayurveda Integr Med. View abstract. Ashwagandha side effects While the side effects of ashwagandha are minimal, some people may experience: Gastrointestinal upset. Vomiting and nausea. ConsumerLab.com uses JavaScript to provide the best possible experience for our content, but your browser has it disabled. J Neurol Sci 2000;176:124-7. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. This is called a medicine interaction. Today, ginseng use is reported to improve the body's resistance to stress and increase vitality, among other uses. There are many conditions garlic has been promoted for: to reduce cholesterol and triglycerides, to prevent cancer, to lower blood sugar levels, and to reduce menstrual pain, among other uses. View abstract. J Ethnopharmacol 1999;64:91-3. 1965;9(1):9-15. Products containing kava may cause liver problems, and taking them with alcohol can increase the risk. The use of the eHealthMe site and its content is at your own risk. Remember that herbal supplements are not subject to FDA oversight and have not usually been tested in clinical studies to prove their effectiveness or safety. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Indian J Physiol Pharmacol. Take extra care if you are taking drugs to help with your thyroid. Biomed Res Int 2015;2015:284154.View abstract. Front Pharmacol 2022;13:901710. It's not clear which of the ingredients had the benefit since ashwaganda is traditionally used in combination with other herbs. Kava has been used to improve sleep, decrease anxiety, and tame nervousness, stress, and restlessness. 8 min read. View abstract. ashwagandha and coumadin interaction. Enter other medications to view a detailed report. The https:// ensures that you are connecting to the Do not use this product if you are pregnant or plan to become pregnant soon. Praveenkumar, V., Kuttan, R., and Kuttan, G. Chemoprotective action of Rasayanas against cyclosphamide toxicity. The interactions between warfarin and medicinal herbs described in the literature have been summarized in this paper relying on Medline database (via PubMed) using the key words: warfarin, herbal supplements and interactions. low blood sugar). Ashwagandha may help the body cope with stress. 2020;72:28-36. View abstract. This product can contain high amounts of iron. Accessed Aug 1, 2022 at https://www.drugs.com/fda-consumer/all-natural-alternatives-for-erectile-dysfunction-a-risky-proposition-349.html, Kratom (mitragyna speciosa) powder products by Gaia Ethnobotanical: Recall - Due to Potential Salmonella Contamination. This information may not fit your specific health circumstances. Phytotherapy Research 1989;3(5):201-206. It may be used by some people to help with rheumatoid arthritis and nerve pain in diabetes, also called diabetic neuropathy.. Evening primrose oil provides fatty acids used by the body for growth. Goldenseal is a flowering herb that grows in the northeast United States. Indian J Exp Biol. They do list some herbs in the drug interactions section (e.g., St. John's Wort) but ashwagandha is not listed. The tannic acid present in some herbs like saw palmetto may slow down the absorption of iron from your body. Speak with a, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Attention deficit-hyperactivity disorder (ADHD), Chronic obstructive pulmonary disease (COPD), Antipsychotic-induced metabolic side effects, Understanding Your Childs Life With ADHD, Think Your Child Has ADHD? Contact your health care provider if you discover that a possible drug interaction may occur between medications and herbal products that you use. You can check other yohimbine interactions here. As a medication, Lexapro does have a list of other medicines where interaction is possible. Archana R, Namasivayam A. Antistressor effect of Withania somnifera. View abstract. If you have blood sugar problems, keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar. However, the practical benefits and risks for people aren't clear yet. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Akhgarjand C, Asoudeh F, Bagheri A, et al. Blog Uncategorized ashwagandha and coumadin interaction Uncategorized ashwagandha and coumadin interaction Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. 18 Herbal Supplements with Risky Drug Interactions. The potential interactions are based on animal studies and individual case reports. interfere with how the drug may be broken down in the body, enhance side effects of prescription medications, block the intended therapeutic effect of a drug. Indian J Thorac Cardiovasc Surg. Garlic has been rarely reported to affect blood clotting and may affect people who take, Patients should be advised to limit their consumption of green tea and green tea extracts during treatment with lisinopril, as these products may lower blood levels of the ACE inhibitor, Dried green tea leaves contain vitamin K, which can increase blood clotting. View abstract. Bonilla DA, Moreno Y, Gho C, Petro JL, Odriozola-Martnez A, Kreider RB. Some people may need to avoid taking Ashwagandha, however, including those who: Additionally, those taking any type of medication or receiving any clinical treatment for anxiety should talk to their doctor about adding Ashwagandha to their wellness regimen. CoenzymeQ10, also known as ubiquinone or CoQ10, is an antioxidant found naturally in the heart, kidney, liver and pancrease, but aging and smoking can deplete these natural stores. In order to do that, you need to be proactive in checking for possible drug interactions yourself in addition to asking your health care provider to screen for interactions. It is often used for menopausal disorders ("hot flashes"), painful menstruation, uterine spasms, and vaginitis. Clot survivors is a support group for people who have survived blood clots. View abstract. View abstract. Biogerontology. / Efficacy of Withania somnifera supplementation on adult's cognition and mood. The bark of yohimbe contains a chemical called yohimbine. Copyright 2023 UpToDate, Inc. and its affiliates and/or licensors. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. Even a glowing, new mom-to-be can be disrupted by a cough, cold, or general aches and pains. Choline vs Alpha-GPC: Which is the Superior Cholinergic? Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Effect of Asian ginseng, Siberian ginseng, and Indian ayurvedic medicine Ashwagandha on serum digoxin measurement by Digoxin III, a new digoxin immunoassay. View abstract. eCollection 2022. View abstract. 1965;9(3):127-136. Some of the interactions between warfarin and medicinal herbs have been well assessed proving that they are closely-dependent. Phytother.Res 2010;24(1):129-135. papain and bromelain), Ginkgo (Ginkgo Biloba) Supplements Review. In some parts of the world, people eat ashwagandha shoots, seeds, and fruit. Association of l-DOPA with recovery following Ayurveda medication in Parkinson's Disease. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Check with your doctor before you combine melatonin with warfarin or other blood thinners. Taking ashwagandha with sedative medications might cause breathing problems and/or too much sleepiness. Consumers need to understand that even though the label may say "natural", these products are not always safe, as demonstrated by "all natural" alternatives sold OTC for erectile dysfunction that the FDA found contained actual prescription medications. Choudhary, M. I., Nawaz, S. A., ul-Haq, Z., Lodhi, M. A., Ghayur, M. N., Jalil, S., Riaz, N., Yousuf, S., Malik, A., Gilani, A. H., and ur-Rahman, A. Withanolides, a new class of natural cholinesterase inhibitors with calcium antagonistic properties. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. p.46-62. Fundukian, L. ed. 2020;40(4):825-829. Review each herbal or prescription drug monograph and check for all possible drug interactions with your healthcare provider. Sleep Med. And if you take a blood thinner, check with your doctor before starting CoQ-10. 1993;31(7):607-611. Dietary Supplement Fact Sheets. Ginger has also been used by some women under medical supervision to reduce severe nausea and vomiting in pregnancy. Baker C, Kirby JB, O'Connor J, Lindsay KG, Hutchins A, Harris M. The perceived impact of ashwagandha on stress, sleep quality, energy, and mental clarity for college students: qualitative analysis of a double-blind randomized control trial. View abstract. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. The use of herbal supplements is becoming a major safety concern because drugherbal interactions can cause serious adverse events. What are the Side Effects of Ashwagandha? J Clin Psychiatry. Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: A double-blind, randomized, placebo-controlled clinical study. Valerian has been used to treat insomnia and anxiety, and people often use it for this effect. Many sources are quick to cover Ashwagandhas potential benefits, and rightfully somodern evidence suggest that the herbal remedy may be useful for managing anxiety, lowering pain and inflammation, and improving heart health. More are needed for more definitive results. Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. She also serves as a preceptor to pharmacy students at the hospital. But menopause can be positive. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ahmad MK, Mahdi AA, Shukla KK, et al. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. hydrochlorothiazide, spironolactone, chlorthalidone). Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). There are many other possible garlic supplement interactions, so be sure to review all possible drug interactions with garlic and speak with your healthcare provider. Of the total drug interactions, 3 are major, 92 are moderate, and 7 are minor. The use of herbal supplements has a long history - dating back thousands of years. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. IV. View abstract. View valerian drug interactions here. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. If you take anti-seizure medications, check with your doctor before using evening primrose oil. View abstract. 3 min read. There are 626 drugs known to interact with Remeron (mirtazapine), along with 13 disease interactions, and 2 alcohol/food interactions. Food Chem.Toxicol. Monitor your blood pressure closely. OTHER NAME(S): Ajagandha, Amangura, Amukkirag, Asan, Asana, Asgan, Ashwagandha has most often been used by adults in doses up to 1000 mg daily, for up to 12 weeks. Others mix 3 grams of ashwagandha powder in warm milk. Animal studies have found that ashwagandha could boost the effects of radiation therapy. Choudhary D, Bhattacharyya S, Joshi K. Body weight management in adults under chronic stress through treatment with ashwagandha root extract: a double-blind, randomized, placebo-controlled trial. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Role of an indigenous drug Geriforte on blood levels of biogenic amines and its significance in the treatment of anxiety neurosis. The phase IV clinical study analyzes what interactions people who take Warfarin sodium and Maca maca have. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. WE CANNOT DIAGNOSE YOU OVER THE INTERNET. 1988;26(11):877-882. Ugeskr Laeger. Minor inhibition was defined by INRs that did not require dosage changes. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat. View abstract. Khattak, S., Saeed, Ur Rehman, Shah, H. U., Khan, T., and Ahmad, M. In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan. 2021;51(4):363-365. If symptoms persist, discontinue use and consult a doctor. 2020;34(5):1041-1059. Major inhibition was defined by the signs of thrombosis, while moderate inhibition was defined by INRs that required a warfarin dosage adjustment. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25. Becoming a Vegetarian: Foods to Choose From. National Library of Medicine View abstract. Clinical characteristics, prescription patterns, and persistence associated with sacubitril/valsartan adoption: A STROBE-compliant study. Bhattacharya, S. K., Bhattacharya, A., Sairam, K., and Ghosal, S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Symptoms of an allergic reaction to Ashwagandha may include: In some cases, herbal remedies can interact with certain medications, including other supplements and OTC and prescription drugs. 2005 - 2023 WebMD LLC. sharing sensitive information, make sure youre on a federal *All products contain less than 0.3% 9THC. Herbal supplements are not subject to review by the FDA and their use can often be risky. I am on the lowest dose too, I have been on warfarin and am now on Xarelto. Mechanism of CoumadinHerbal Interactions. Potential interactions between alternatives therapies and warfarin. J Ethnopharmacol. Effect of Ashwagandha (Withania somnifera Dunal) on the process of ageing on human volunteers. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Fuladi S, Emami SA, Mohammadpour AH, Karimani A, Manteghi AA, Sahebkar A. Indian J Med Res 2015 Jan;141(1):100-6. blood glucose). Always follow your doctor's directions. Cent.Nerv.Syst.Agents Med.Chem. Minor potentiation was defined as an INR that does not require a dosage adjustment. Accessed Aug 1, 2022 at https://ods.od.nih.gov/, "All Natural" Alternatives for Erectile Dysfunction: A Risky Proposition. If you take a drug meant to suppress your immune systems, such as methotrexate or mycophenolate, they may have conflicting effects. Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will posts that exceed 2,500 characters. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Another way to take the two together is with capsules. Check other possible ginger-drug interactions here. View abstract. Call your doctor immediately if you have fever, joint pain, bleeding, skin rash or itch, appetite loss, fatigue, nausea/vomiting, stomach pain, dark colored urine, light colored stools, and/or yellowing of the skin/eyes; these may be signs of liver toxicity. 8-19-2005;334(1):276-287. V. The effect of total alkaloids (ashwagandholine) on the central nervous system. Altern Med Rev 2000;5:334-46. The references on the analyzed literature have been investigated in order to collect the existing data. There are 645 drugs known to interact with methotrexate, along with 5 disease interactions, and 3 alcohol/food interactions. PLoS One 2009;4:e6628. There are over 100 possible drug interactions with goldenseal, have your pharmacist check for drug interactions with all your medicines. Cureus. Yes, the effectiveness of warfarin (Coumadin), anisindione (Miradon) and other anticoagulant drugs prescribed to help prevent blood clots can be impacted by taking supplements. All rights reserved. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Enter other medications to view a detailed report. If you take drugs or herbs that may have blood thinner effects (for example: warfarin), or take NSAIDs like ibuprofen or naproxen, check with your health care provider before using evening primrose oil. Do not stop using any medications without first talking to your doctor. There is no drug interaction reported. Can you get ashwagandha naturally from foods? PMC On xarelto, I've used plenty of herbs, including ashwagandha with no problems. 2008;6:14. Phytother Res 1991;5:111-14. Effect of Indian Ayurvedic medicine Ashwagandha on measurement of serum digoxin and 11 commonly monitored drugs using immunoassays: study of protein binding and interaction with Digibind. Can You Take A Z-Pak If You Have A Penicillin Allergy? Echinacea is also known as the American Cone Flower, Black Susan, or Purple Coneflower. People use ashwagandha for other health conditions, including anemia. There are many different types of choline supplements, but Alpha-GPC may just be superior. Hu Z, Yang X, Ho PC, Chan SY, Heng PW, Chan E, Duan W, Koh HL, Zhou S. Drugs. Evening primrose is a flowering plant known by other names such as Oenothera biennis, scabish, or king's cureall. Taking ashwagandha with thyroid hormone pills might cause too much thyroid hormone in the body, and increase the effects and side effects of thyroid hormone. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Ginger is a commonly used flavoring agent, food product, and herbal supplement. Acta Pol.Pharm. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: a randomized controlled trial. Go to the ER right away. J Obstet Gynaecol Res 2021. Tumori 8-31-1994;80(4):306-308. Ginkgo interacts with over 290 drugs; have a pharmacist check for interactions before use. Unauthorized use of these marks is strictly prohibited. Indian J Exp Biol. Therapy with yohimbine is generally not recommended in patients with hypertension, angina, or heart disease because it has a stimulatory effect and can lead to high blood pressure and a rapid heart rate. Of course, theres more to the story that needs to be considered before adding a new supplement to your daily wellness routine. Indian J Pharmacol. Available for Android and iOS devices. However, the practical benefits and risks for people. 2003;19(3):211-222. These products are intended for use and purchase only by persons 21 and older as in selected States. In most cases, Ashwagandha has shown to have little to no risk of adverse effects. Because it can be affected by a large number of herbs, supplements and foods, it's important to consult your physician before taking any supplement with warfarin. 1985;23(4):177-183. We can, however, make some educated guesses on drug interactions based on ashwagandha works, and the effects it is known to have. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Evaluation of the efficacy of withania somnifera (ashwagandha) root extract in patients with obsessive-compulsive disorder: a randomized double-blind placebo-controlled trial. The drug interaction may be insignificant and no change may be needed; on the other hand, the interaction could be of concern and the herbal supplement may need to be discontinued, a drug dose changed, or a new medicine selected. The site is secure. Ashwagandha has active ingredients of ashwagandha. Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. Ashwagandha side effects are rare and almost always mild. Some people use between 1 to 6 grams of the whole herb daily. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. In our latest question and answer, the pharmacist discusses whether or not ashwagandha supplements interact with prescription drugs. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Does Remeron interact with my other drugs? Ashwagandha contains several active constituents including: The mechanism of how ashwagandha works, for all of its purported benefits, is not well understood. Jahanbakhsh SP, Manteghi AA, Emami SA, Mahyari S, et al. All rights reserved. Save money by finding high-quality products at lower cost. View abstract. Drugs.com. I suffer from depression, stress and anxiety but I Can I take Benadryl (Diphenhydramine) and Claritin (Loratadine) together? I want I have bad allerg Can a diabetic who is dehydrated take oral rehydration sachets? All rights reserved. You can look up your blood thinner at https://www.drugbank.ca/drugs/DB06228 (that's the page for Rivaroxaban / Xarelto but you can search for your blood thinner at the top right). The comparative effect of milk fortified with Aswagandha, Aswagandha and Punarnava in children - a double-blind study. WebMD says it can interact with thyroid medicine, anti depressants, and immunosuppressants, it doesn't list any blood thinners (link at https://www.webmd.com/vitamins/ai/ingredientmono-953/ashwagandha) direebn 3 days ago Liver Int. The case reports with severe adverse effects such as spontaneous postoperative bleeding, formation of hematomas, hematemesis, melena, thrombosis, subarachnoid hemorrhage and/or subdural hematomas after concomitant use of warfarin and the medicinal herbs: Panax ginseng, Hypericum perforatum, Salvia milthiorizza, Gingko biloba, Serenoa repens, Angelica sinensis, Vaccinium species, Allium sativum, Zingiber officinale, Tanacetum parthenium, Lucium barbarum, Matricaria chamomilla, Boswellia serrata and Camellia sinensis have been estimated. J Clin Med 2021;10(16):3644. medicinal mushroom and nootropic ingredients. Signs of a very bad reaction. One study, published in Phytotherapy Research, reported that ashwagandha supplementation reduced blood sugar and A1c levels, although this was a relatively small study. Can You Take Ashwagandha And Orilissa Together? It is very widely utilized as a dietary supplement and used for a number of purported medical benefits, including: As ashwagandha is a botanical, it appears to have many different active components and a complex mechanism of action for how it works. Syst Rev. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. View abstract. These products are not intended to diagnose, treat, cure, or prevent any disease. drugs for diabetes and blood pressure). National Institute of Health (NIH). Women who are breastfeeding should also not use the herb.. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. View abstract. Sriranjini SJ, Pal PK, Devidas KV, Ganpathy S. Improvement of balance in progressive degenerative cerebellar ataxias after Ayurvedic therapy: a preliminary report. Ashwagandha, also known as 'Indian Ginseng' is an evergreen shrub indigenous to India, the Middle East, and some parts of Africa. * We do not sell or share your personal information with anyone else, ever. View abstract. 2018 Mar;24(3):243-248. Potential herb-drug interactions are of a major safety concern, especially for drugs with narrow therapeutic indices like warfarin, which can lead to severe adverse reactions that are sometimes life-threatening. View abstract. View abstract. [Herbal medicines--evidence and drug interactions in clinical practice]. Staff. J Ethnopharmacol 1999;67:233-39. Deocaris, C. C., Widodo, N., Wadhwa, R., and Kaul, S. C. Merger of ayurveda and tissue culture-based functional genomics: inspirations from systems biology. Drug interactions with ginger are not well documented; however, it is known to inhibit thromboxane synthetase, which can prolong bleeding time and may rarely cause interactions with anticoagulants like warfarin, aspirin, or other blood thinners. 2023 eHealthMe.com. Im on warfarin, so there are a ton of drug interactions. Still, best to proceed with caution. Phytother Res. If saw palmetto is combined with estrogens or oral contraceptives, the effectiveness of the hormonal therapies could be reduced. levothyroxine, desiccated thyroid) could potentially increase thyroid hormone levels too much, increasing the risk of side effects. Cureus. Change in balance, feeling shaky, or unsteady, Not able to think clearly or change in thinking, US Department of Defense Dietary Supplement Resource, https://www.opss.org/article/ashwagandha-dietary-supplement-products, This generalized information is a limited summary of diagnosis, treatment, and/or medication information. Kaur, K., Rani, G., Widodo, N., Nagpal, A., Taira, K., Kaul, S. C., and Wadhwa, R. Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha. Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. Like easy bruising, bleeding gums, etc. MeSH First and foremost, I want to point out this it can tricky to determine whether or not a dietary/herbal supplement will interact with prescription drugs due to a general lack of studies on the matter.

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