The aim of this systematic literature review is to describe and analyse the psychometric properties of the PGA. , Saad-Magalhes C , Suriano A , Liberati A allergy hx phenothiazines, cns depressants and stimulants withheld 48 hours prior. et al. The LUMINA (Lupus in Minorities: Nature versus Nurture) study and other trials have offered evidence of a decrease in flares and prolonged life in patients given hydroxychloroquine, making . Physician's Global Assessment (PGA) score 1.0 on a 0 to 3 visual analog scale. et al. Your comment will be reviewed and published at the journal's discretion. The aim of this systematic literature review (SLR) is to describe and analyse the psychometric properties of PGA. . The PGA was developed on a 0 to 3 scale as part of the Lupus Activity Index. The PGA is a valid instrument but has variable reliability; its scoring should be standardized. Each study was examined in order to extract psychometric property data on the PGA according to the OMERACT Filter methodology version 2.1 [18]. The Patient's Global Assessment Scale (PGA) is the PRO counterpart to the Physician's Global Assessment Scale or Investigator's Global Assessment Scale (PGA-IGA). , Glassman DS , Gladman DD Thank you for submitting a comment on this article. The company serves physicians and patients. , Gladman DD Observed and articulated management issues and responses. The PGA also showed good predictive validity, as it correlated significantly with measures of future outcomes, such as quality of life or laboratory exams, but no study has currently evaluated its correlation with measures of damage. , Block JA The OMERACT defines an instrument as an outcome measure if it passes the three pillars of evidence: truth (that refers to validity), discrimination (that includes reliability and responsiveness) and feasibility. The Senior Lead will be responsible for: Managing end to end production, governance and controls of Derivatives Standardized and Advanced RWA, and SLE Actuals. The .gov means its official. Kiani AN 8600 Rockville Pike , Koutsoviti S ECG - correct answer no sleep the night before, meals allowed, no stimulants/tranquilizers for 24-48 hours before. physician's global assessment (PGA) of disease activity in SLE. Construct validity is the degree to which the PGA relates to other instruments that measure the same concept [18]. SLE has protean and often complex manifestations, necessitating careful clinical assessment. watch for seizures after the procedure. Currently no agreement has been reached on which scale should be used: a pointed scale with anchored values (0, 1, 2, 3) or a centimetric scale with all values between 0.0 and 3.0. PMC Arthritis Res Ther. , Engel SM Trusted for over 30 years to provide and transform technology into complete solutions that advance the value of IT. The PGA is a well accepted and commonly used scale for evaluating treatment response in clinical trials both in adults and children. SELENA SLEDAI4. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of multifactorial origin that can affect any organ or organ system, resulting in a broad spectrum of clinical manifestations ranging from dermatological involvement to multi-organ failure with episodes of relapses and remissions. Newark, New Castle, USA, March 03, 2023 (GLOBE NEWSWIRE) -- The global complement-targeted therapeutics market is expected to grow at a CAGR of 8.9% from 2022 to 2030, owing to the rising . Conclusion: Management of systemic lupus erythematosus (SLE) often depends on disease severity and disease manifestations, [] although hydroxychloroquine has a central role for long-term treatment in all SLE patients. Strength. et al. , Bentow C et al. The assessment of disease activity in SLE is particularly challenging. , Socher SA PGA is a valid, responsive and feasible instrument, while its reliability was impacted by the scale adopted, suggesting the major need for a standardization of its scoring. , Arbab-Zadeh A AU - Louthrenoo, Worawit. Face validity. The aim of this systematic literature review is to describe and analyse the psychometric properties of the PGA. MeSH The Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus (PISCOS) study aimed to obtain an evidence-based and expert-based consensus standardisation of the Physician Global Assessment (PGA) scoring of disease activity in systemic lupus erythematosus (SLE). 215 (FIVE YEARS 146) H-INDEX. Eudy AM All articles published through 1 July 2019 in PubMed were screened, with no limitation on year of publication, language or patients age. et al. 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Conducting medical monitoring, safety review, narrative writing and etc.. Perform medical assessment of individual . Touma Z , Friebus-Kardash J Search for other works by this author on: Rheumatology Unit, AOU University Clinic and University of Cagliari, Department of Medical Sciences and Public Health, Cagliari, Italy, Centre Hospitalier Universitaire de Dijon, Hpital Franois-Mitterrand, service de mdecine interne et maladies systmiques (mdecine interne, 2) et Centre dInvestigation Clinique, Service de rhumatologie, Hpitaux Universitaires de Strasbourg, Universit de Strasbourg, Centre National de Rfrence des Maladies Systmiques et Autoimmunes Rares Est Sud-Ouest (RESO). , Chan KL Beaton DE Brunner HI If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week's collection. This site needs JavaScript to work properly. , Devilliers H et al. Physician Global Assessment (PGA) is a visual analogue score (VAS) that reflects the clinician's judgment of overall Systemic Lupus Erythematosus (SLE) disease activity. et al. Systemic lupus erythematosus (SLE), is the most common type of lupus. The Physician Global Assessment (PGA) is a visual analogue score that reflects the clinician's judgement of overall SLE disease activity. doi: 10.1136/lupus-2022-000700. When expanded it provides a list of search options that will switch the search inputs to match the current selection. The interobserver agreement between physician (PGA) and patient (PtGA) global assessment for acne and psoriasis was good, reflected by the weighted Cohen (acne, = 0.68; psoriasis, = 0.70) (eTable in the Supplement). In support of its face validity, the PGA was used to define the disease activity score in all 91 studies retrieved by the literature search, having a role as an outcome measure as well as a comparator to assess the validity of other indices. , Lerman RH Petri M The PGA is usually reported by experts as allowing exhaustive coverage of the concept of disease activity in SLE [20, 108]. , Chizzolini C , Ibanez D Tel: 03 88 12 84 74; Fax: 03 88 12 82 90; E-mail: Measuring disease activity in adults with systemic lupus erythematosus: the challenges of administrative burden and responsiveness to patient concerns in clinical research, Patterns of disease activity in systemic lupus erythematosus, Novel evidence-based systemic lupus erythematosus responder index, Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus, Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus, Treatment target in newly diagnosed systemic lupus erythematosus, 10 most important contemporary challenges in the management of SLE, Measurement of systemic lupus erythematosus activity in clinical research, Definition, incidence, and clinical description of flare in systemic lupus erythematosus. A good responsiveness for PGA was shown in eight studies. , Klein-Gitelman MS , Longenecker JC The Physician Global Assessment (PGA) of treatment response measures the overall response to treatment as assessed by the physician. , Adamichou C

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